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. 2022 May 29;14(1):2078612. doi: 10.1080/19490976.2022.2078612

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Noninvasive multidimensional prediction of nonalcoholic steatohepatitis (NASH) using three microbial families and potential clinical variables in all subjects as well as the high carbohydrate (HC), and low carbohydrate (LC) intake groups (non-NASH vs. NASH). The receiver-operating characteristic (ROC) curve was designed for detecting NASH among study subjects with biopsy-proven NAFLD. Area under receiver-operating characteristic curves (AUROC) analyses including clinical variables (BMI, age, and sex) (blue) vs. those also including the three microbial families (Enterobacteriaceae, Ruminococcaceae, and Veillonellaceae) in addition to clinical variables (BMI, age, and sex) (red) plotted for the diagnosis of NASH in (a)all subjects as well as, (b) the HC, and (c) LC groups. P values were calculated using the DeLong test.