. 2022 May 31;12(25):16194–16202. doi: 10.1039/d2ra02457h

Comparison of the reported methods with the proposed method for the determination of AAPs in human plasma.

Analytes	Sample volume	LOQ	Extraction recovery	Method	Ref.
Clozapine, lanzapine, quetiapine	500 μL	2.0 ng mL⁻¹	≥0.79	SPE-GC-MS/MS	35
Amisulpride, aripiprazole, clozapine, olanzapine, quetiapine, risperidone sulpiride	200 μL	1.0–5.0 ng mL⁻¹	≥0.67	LLE-LC-MS/MS	23
Amisulpride, olanzapine, aripiprazole, paliperidone ziprasidone	20 μL	0.1–9.0 ng mL⁻¹	≥0.86	PP-UPLC-MS/MS	24
Olanzapine, clozapine, quetiapine	—	1.25–40 ng mL⁻¹	≥0.93	Column-switching -HPLC-UV	36
Olanzapine, quetiapine, clozapine, haloperidol, chlorpromazine	200 μL	0.05-1 ng mL⁻¹	—	MEPS LC-MS/MS	37
Clozapine, risperidone, quetiapine, aripiprazole, olanzapine	450 μL	0.5–1.0 ng mL⁻¹	≥0.51	LLE-LC-MS/MS	25
Risperidone, clozapine, quetiapine, aripiprazole	1500 μL	4.7–18.8 ng mL⁻¹	≥0.80	SPE-HPLC-DAD	38
Olanzapine, risperidone, paliperidone, clozapine, quetiapine, ziprasidone aripiprazole	90 μL	1.0 μg mL⁻¹	≥0.58	PS-SPE-UPLC-UV	This paper