Table 5.
Major and minor criteria for high haemorrhagic risk at the time of PCI
| Major criteria | Minor criteria |
|---|---|
| Age >75 years | |
| Anticipated need for long-term anticoagulant therapya | |
| Severe or terminal chronic renal impairment (eVFR < 30 mL/min) | Moderate chronic renal impairment (eVFR 30–59 mL/min) |
| Haemoglobin <11 g/dL | Haemoglobin 11–12.9 g/dL in males or 11–11.9 in females |
| Spontaneous bleeding that has required transfusion during hospitalization in the past 6 months or at any time, if recurrent | Spontaneous bleeding that has required hospitalization or transfusions in the last 12 months that do not satisfy the major criteria |
| Moderate or severe basalb platelet penia (platelet count < 100 × 109/L) | |
| Haemorrhagic diathesis | |
| Liver cirrhosis with portal hypertension | |
| Long-term use of corticosteroids or NSAID | |
| Active neoplasmc (with the exception of skin neoplasms other than melanoma) in the last 12 months | |
| Previous spontaneous intraparenchymal haemorrhage (at any time) Traumatic intraparenchymal haemorrhage (in the last 12 months) | Any ischaemic stroke in any period of time that does not meet the major criteria |
| Presence of cerebral AVM | |
| Ischaemic stroked of severe or major degree in the last 6 months | |
| Non-deferrable major surgery during DAPT | |
| Recent major surgery or major trauma in the last 30 days |
DAPT, dual antiplatelet therapy; eVFR, estimated glomerular filtration rate; HBR, high haemorrhagic risk; MAV, arteriovenous malformation; NSAID, non-steroidal anti-inflammatory drugs.
a
Except for vascular protection doses.
b
Basal thrombocytopaenia is defined as thrombocytopaenua before coronary angioplasty.
c
Active neoplasm is defined as such if diagnosed in the last 12 months and/or during therapy (including surgery, chemotherapy, or radiotherapy).
d
On the basis of the National Institutes of Health Stroke Scale ≥5.