Table 2.
Safety concerns
| Safety concerns | Responses, n | Comments |
|---|---|---|
| Increased cholesterol levels | 10 | |
| Increased heart rate | 3 | 2 of 3 responses reported a normalization over time |
| Strong side effects | 2 | Brain fog, ‘keto flu’ |
| Increase in creatinine | 2 | 2 of 2 responses reported a return back to levels before starting the diet |
| New incidence of kidney stones | 1 | Incidental finding |
| Increase in serum uric acid | 1 | |
| Increased serum bilirubin levels | 1 | Normalized over time |
| Decreased international normalized ratio levels | 1 | Participant on warfarin therapy prior to the start of the diet. Warfarin dose was adjusted accordingly |
| Decreased vitamin B levels | 1 | |
| Decline in BP | 1 | Consecutive dizziness. Normalized after adjusting BP medication |
Full list of changes on KDIs that have raised safety concerns for the participants or their doctors.