Table 3.
Description of studies and data used in empirical review
| Study | N | Age (years) | Immune status | Genotype | Range (days) | Mean (days) | Median (days) |
|---|---|---|---|---|---|---|---|
| Atmar & Estes (2008) [8]a | 16 | 18–50 | + | GI.I | 8–54 | 28·6 | 27 |
| Florescu et al. (2008) [36]b | 1 | 1·8 | − | 240 | 240 | 240 | |
| Gallimore et al. (2004) [35]c | 1 | Child | − | rGII.3 | 156 | 156 | 156 |
| Goller et al. (2004) [51]d | 1 | 18 | + | n.r. | 8 | 8 | 8 |
| Goller et al. (2004) [25]e | 9 | 79–94 | + | GII | 2–20 | 10·7 | 10 |
| Kirkwood & Streitberg (2008) [43]f | 9 | 0–2 | + (6), − (3) | GII.4, GII.6 | 2–100 | 30·8 | 15 |
| Lee et al. (2008) [37]b | 1 | 0·8 | − | GII.2 | 114 | 114 | 114 |
| Leon et al. (2011) [24]a | 13 | 18–48 | + | GI.1 | 8–35 | 21·3 | 21 |
| Ludwig et al. (2008) [41]g | 9 | 0–16 | − | GII.4, GII.3 | 22–433 | 95·7 | 46 |
| Murata et al. (2007) [14]h | 23 | 0–3 | + | n.r. | 5–47 | 17·3 | 16 |
| Nilsson et al. (2003) [38]i | 1 | 65 | − | GII | 670 | 670 | 670 |
| Parashar et al. (1998) [52]j | 1 | Adult | + | GII | 10 | 10 | 10 |
| Schorn et al. (2010) [39]k | 9 | 23–59 | − | GII.4, GII.7 | 97–898 | 305 | 230 |
| Siebenga et al. (2008) [49]l | 8 | 0–69 | − | GII.4, GIIb–GII.3 | 35–182 | 89·3 | 77 |
| Seitz et al. (2011) [26]a | 9 | 18–50 | + | GI.1 | 4–34 | 17·6 | 15 |
| Simon et al. (2006) [42]m | 12 | 0–24 | − | n.r. | 3–140 | 40·4 | 23 |
| Tu et al. (2008) [9]e | 14 | 63–93 | + | GII | 8–44 | 25·2 | 25·5 |
| Westhoff et al. (2009) [40]k | 2 | 73 | − | GII | 90–165 | 127·5 | 127·5 |
| C. L. Moe, unpublished (1)a | 22 | 18–50 | + | GI.1 | 8–20 | 8·3 | 7 |
| C. L. Moe, unpublished (2)a | 9 | 18–50 | + | GII.2 | 3–20 | 6·9 | 5 |
+, Immunocompetent; –, immunocompromised; n.r., not reported; r, recombinant.
a Challenge study. b Case study of infant transplant recipient. c Case study of child with genetic disorder.
d Investigation of healthcare worker. e Outbreak investigation in an elderly care facility. f Prospective hospital study. g Retrospective study of paediatric oncology patients. h Outpatients at a paediatric clinic. i Case study. j Outbreak investigation of food handlers. k Study of transplant recipients. l 2-year hospital survey. m Outbreak investigation in paediatric oncology and haematology unit.