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. 2022 Mar 9;77(6):1685–1693. doi: 10.1093/jac/dkac070

Table 1.

Overview of MTBC members included in this study

Group MTBC membera Lineageb Lineage synonymc Major spoligotype(s)c No. Resistance (%) by resistance type
DS-TB DR-TB MDR-TB XDR-TB
A M. africanum 5 West African I AFRI2 2 100 0 0 0
6 West African II AFRI1 3 100 0 0 0
M. bovis d 2 0 100 0 0
M. bovis BCGe 1 0 100 0 0
M. caprae 1 100 0 0 0
M. microti 1 100 0 0 0
M. pinnipedii 1 100 0 0 0
B M. tuberculosis 2 East Asian Beijing 63 17 2 51 31
3 East African-Indian CAS 12 92 0 8 0
4 Euro-American Haarlem, LAM, T, X 113 42 9 36 13
7 3 100 0 0 0
C M. tuberculosis 1 Indo-Oceanic EAI 127 64 10 24 2
D M. canettii f 21 0 100 0 0
Probably resistantg M. tuberculosis 1 Indo-Oceanic EAI 4 100 0 0 0
2 East Asian Beijing 2 50 0 50 0
a

In accordance with current CLSI guidelines, we considered M. canettii to be part of MTBC, although this classification is disputed.54,55

b

Based on Coll et al.29

c

Based on Gagneux & Small.56

d

Largely intrinsically resistant to pyrazinamide.31

e

Intrinsically resistant to pyrazinamide and cycloserine.52

f

Intrinsically resistant to pyrazinamide.31

g

See Table 2 for more details.