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Cortisol synthesis inhibitors and receptor blockers. Sites of inhibition are demarcated by “X,” color matched to the boxes below with the corresponding drug. Abbreviations17α-OH, 17α hydroxyprogesterone; 21-OH, 21-hydroxylase; 3β HSD, 3β-hydroxysteroid dehydrogenase; ACC, adrenal cortical carcinoma; CS, Cushing syndrome; CYP11B1, cytochrome P450 family 11 subfamily B member 1; CYP11B2, cytochrome P450 family 11 subfamily B member 2.
