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. 2022 Mar 22;77(6):1600–1610. doi: 10.1093/jac/dkac084

Figure 4.

Figure 4.

Mutations detected in OprD, regulators of efflux systems and gene expression heat map for efflux pumps MexAB-OprM, MexCD-OprJ, MexEF-OprN and MexXY. MP, mutation pattern; NM, no mutation; _, absence. MP1 = D43N, S57E, S59R, E202Q, I210A, E230K, S240T, N262T, A267S, A281G, K296Q, Q301E, R310G, V359L, 372(V-DSSSSYAGL-)383. MP2 = K2E, D43N, S57E, S59R, E202Q, I210A, E230K, S240T, N262T, A267S, A281G, K296Q, Q301E, R310G, V359L, 372(V-DSSSSYAGL-)383. MP3 = K2E, T103S, K115T, F170L, E185Q, P186G, V189T, R310E, A315G. MP4 = S57E, S59R, V127L, E185Q, P186G, V189T, E202Q, I210A, E230K, S240T, N262T, T276A, A281G, K296Q, Q301E, R310E, A315G, L347M, 372(V-DSSSSYAGL-)383. MP5 = T103S, K115T, F170L, E185Q, P186G, V189T, R310E, A315G.