Table 2.

Relationship between the number of mutated genes and ciprofloxacin MIC

QRDR mutations	Number of strains	MIC (mg/L)	Mean MIC (mg/L)
One mutation
gyrB	1	1.5	0.75
parC	1	0.5
parE	2	0.5–0.5
Two mutations
gyrB + parC	1	0.5	9.06
gyrB + parE	2	0.5–32
parC + parE	2	0.5–2
gyrA + parE	2	1.0–4
gyrA + parC	1	32
Three mutations
gyrA + gyrB + parE	2	1–32	20
gyrA + parC + parE	2	32–32
gyrB + parC + parE	1	3
Four mutations
gyrA + gyrB + parC + parE	1	32	32