| Key points 5-AminoLevulinic Acid (5-ALA) |
|---|
| - 5-ALA is metabolized to PpIX and accumulates in tumor cells |
| - PpIX absorbs violet-blue light and transmits in the red spectrum of 600 nm to 650 nm with peak emission at 635 nm |
| - 5-ALA has been shown to improve glioma resection rates and progression-free survival rates |
| - Literature is sparse concerning 5-ALA usage during PitNET surgery. No strong added benefit for pituitary adenoma surgery has been proven yet |
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