Table 3.

Nonirritating concentrations for platinum agent skin testing

Agent	SPT dilutions (mg/mL)	IDT dilutions (mg/mL)a
Carboplatin	10	0.1
		1
		5b
Oxaliplatin	5	0.05
		0.5
		5
Cisplatin	1	0.01
		0.1
		1

Variations exist: the European Academy of Allergy and Clinical Immunology (EAACI) recommends concentrations of 10 and 1 mg/mL for carboplatin SPT and IDT and 1 and 0.1 mg/mL for oxaliplatin and cisplatin SPT and IDT [73]

SPT skin prick test, IDT intradermal test

^aFor intradermal tests, 0.02–0.03 mL is used

^bReported concentrations for the last IDT step include 3, 5, and 10 mg/mL; 10 mg/mL has been reported to cause local skin necrosis and is therefore not recommended