Table 2.
Multivariable analysis for prediction of symptomatic venous thromboembolism, based on variables available upon hospital presentation
| Variable | Frequency (%) or median (IQR) | Confirmed VTE | |
|---|---|---|---|
| Odds ratio (95% CI) | p value | ||
| Obesitya | 766 (18.6%) | 1.50 (1.11–2.02) | < 0.01 |
| Atrial fibrillation/flutter | 140 (3.4%) | 0.30 (0.09–0.99) | 0.04 |
| Previous use of beta blocker | 732 (17.8%) | 0.73 (0.50–1.07) | 0.11 |
| Ex-smoker | 644 (15.6%) | 1.44 (1.03–2.01) | 0.03 |
| Surgery in previous 90 days | 101 (2.5%) | 2.20 (1.14–4.23) | < 0.01 |
| Temperature (°C)bc | 36.5 (36.0, 37.2) | 1.41 (1.22–1.63) | < 0.01 |
| SF ratiobd | 428.6 (317.9, 452.4) | 0.87 (0.83–0.93) | < 0.01 |
| D-dimer/maximum reference valueb | |||
| 1–1.9x | 911 (22.1%) | 1.32 (0.83–2.09) | 0.239 |
| 2–3.9x | 575 (13.9%) | 1.19 (0.72–1.96) | 0.486 |
| 4–9.9x | 304 (7.3%) | 2.16 (1.26–3.67) | < 0.01 |
| ≥ 10x | 804 (19.5%) | 1.89 (1.18–3.01) | < 0.01 |
| Lactatebe | 1.4 (1.1, 1.9) | 1.10 (1.02–1.19) | 0.01 |
| C-reactive protein (mg/L)bd | 74.4 (34.0, 134.1) | 1.09 (1.01–1.18) | 0.01 |
| Neutrophils’ countbf | 5,045.0 (3,400.0, 7,613.8) | 1.04 (1.005–1.075) | 0.02 |
| Prophylactic use of anticoagulant | 3,247 (78.8%) | 0.20 (0.15–0.26) | < 0.01 |
| Full-dose anticoagulation for prophylaxis | 498 (12.1%) | NA | 0.95 |
IQR Interquartile range, SF ratio oxygen saturation/inspired oxygen fraction
aBMI (Body mass index) > 30 kg/m2
bData regarding hospital presentation
cIncrement of 1.0 ºC
dIncrement of 50 units
eIncrement of 1 unit
fIncrement of 1000 units