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. 2022 May 27;81:104085. doi: 10.1016/j.ebiom.2022.104085

Table 1.

Changes in gut microbial metabolites in representative diseases.

Disease Metabolites Levels in patients
Inflammatory Bowel Disease Primary bile acids Increased6

Fatty Liver N, N, N-trimethyl-5-aminovaleric acid Increased7

Hepatocellular carcinoma Linoleic acid and phenol Decreased24

Blood pressure Acetate, butyrate, and propionate Increased24

Chronic kidney disease Indole, indole-3-carboxaldehyde and indole-3-propionic acid Decreased8

Obesity
SCFA Decreased10
Succinic acid Increased12

Type 2 diabetes/prodromal diabetes Imidazole Propionate Increased16