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. 2022 Apr 27;28:859–874. doi: 10.1016/j.omtn.2022.04.012

Figure 6.

Figure 6

Abnormalities in plasma guanidino compounds are improved with ARG1 mRNA administration

(A) Argininic acid, (B) creatine, (C) guanidinoacetic acid (GAA), and (E) keto-arginine are all reduced with mRNA ARG1 administration, while (D) homoarginine remains reduced (n = 6–11 per group). ARG1, arginase 1; mRNA, messenger ribonucleic acid. Data are represented as mean ± SD.