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. 2022 May 21;8(5):e09502. doi: 10.1016/j.heliyon.2022.e09502

Figure 10.

Figure 10

a) Silhouette plot of samples after GFS normalisation (θ1 = 5%, θ2 = 15%). Silhouette scores of some subjects in cluster 1 are negative, indicating that they are closer to cluster 0. b) Venn diagram of gene signatures found globally and locally per cluster. Global DEGs are heavily overlapping with DEGs from the male-dominant cluster 1, indicating the global signatures are skewed by male subjects as well.