Figure 6.
Summary of data for AKI00000062a.A, structure of AKI00000062a. B, enzymatic profiling of AKI00000062a versus CK1γ family kinases. C, kinome tree representation of kinases with PoC <10 when AKI00000062a was profiled at 1 μM versus 403 WT kinases. D, specific kinases (n = 17) with PoC <10 in kinome-wide profiling. E, Nanoluc-CK1γ2 NanoBRET curve, and corresponding IC50 value for AKI00000062a. CK1γ, casein kinase 1γ; PoC, Percent of Control.