Fig. 5.

Overexpression of meiotic cDNA libraries reveals a subset of mitochondrial genes that are detrimental to competitive fitness. a) Overlap between genes identified in this study (SK1 background) to be detrimental for competitive fitness and genes identified in other studies (S288C background) using a similar assay (Douglas et al. 2012; Arita et al. 2021). b) GO enrichment analysis of the 760 genes found to be unique to this study in (a). Only GO terms that contain <1,000 genes are shown. The fold enrichment is shown on the x-axis and the size of each point indicates the negative log10 of the adjusted p-value. CC, cellular component; BP, biological process; MF, molecular function. c) Of the 760 genes found to be detrimental for competitive fitness in our study, 215 are annotated as being mitochondria-related and 43 have a predicted MTS.