Lipo-PEG-apt metabolic and histologic analysis in rat liver and kidney. a. Levels of ALT (alanine aminotransferase), AST (aspartate aminotransferase), ALB (albumin), ALP (alkaline phosphatase), DBIL (direct bilirubin), TBIL (total bilirubin), r-gt (glutamyl transpeptidase), TBA (total bile acid), TP (total protein) in liver. b. Levels of BUN (urea nitrogen), CR (serum creatinine), UA (uric acid), and TP (total protein) in serum. c. The sections of the liver and kidney were stained with hematoxylin and eosin. Scale bars represented 50 μm.