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. 2022 May 31;176(8):787–796. doi: 10.1001/jamapediatrics.2022.1622

Table 1. Incident Cases and Deaths of Neonatal Preterm Birth in 1990 and 2019 and Their Change Trends From 1990 to 2019.

Characteristic 1990 2019 Relative change, 1990-2019
Incident cases, No. × 105 (95% UI) Deaths, No. × 103 (95% UI) Incident cases, No. × 105 (95% UI) Deaths, No. × 103 (95% UI) Incident cases, % Deaths, %
Overall 160.62 (159.46-161.90) 1269.04 (1166.14-1383.98) 152.17 (151.11-153.20) 663.52 (560.96-788.95) −5.26 −47.71
Sex
Female 73.42 (72.63-74.30) 560.11 (511.83-613.97) 69.75 (68.97-70.43) 279.57 (237.91-327.32) −5.00 −50.09
Male 87.19 (86.34-88.05) 708.93 (644.55-781.04) 82.42 (81.70-83.18) 383.95 (321.74-463.85) −5.47 −45.84
SDI region
Low NA 250.36 (221.71-283.47) NA 261.93 (214.37-321.60) NA 4.62
Low-middle NA 474.63 (426.84-532.36) NA 237.06 (196.74-280.55) NA −50.05
Middle NA 376.48 (348.51-406.02) NA 124.81 (105.33-147.61) NA −66.85
Middle-high NA 135.26 (122.63-148.39) NA 27.98 (23.74-32.93) NA −79.31
High 9.72 (9.63-9.81) 31.69 (29.80-33.81) 9.11 (9.01-9.21) 11.31 (10.07-12.66) −5.00 −64.31
GBD region
Andean Latin America 1.10 (1.05-1.15) 10.93 (9.51-12.51) 1.08 (1.04-1.13) 4.08 (2.93-5.48) −1.78 −62.67
Australasia 0.22 (0.21-0.23) 0.65 (0.60-0.71) 0.27 (0.26-0.29) 0.25 (0.20-0.31) 25.30 −61.37
Caribbean 1.30 (1.26-1.34) 6.07 (5.28-6.96) 1.23 (1.18-1.27) 3.84 (2.78-5.23) −5.15 −36.68
Central Asia 1.40 (1.36-1.45) 9.34 (8.15-10.65) 1.26 (1.22-1.30) 5.66 (4.63-6.90) −10.16 −39.43
Central Europe 1.21 (1.18-1.23) 7.81 (7.36-8.29) 0.81 (0.79-0.82) 1.21 (0.92-1.52) −33.16 −84.55
Central Latin America 4.23 (4.15-4.31) 39.64 (34.90-44.39) 4.07 (3.99-4.15) 11.58 (8.85-14.60) −3.71 −70.78
Central Sub-Saharan Africa 2.91 (2.79-3.03) 25.74 (19.70-32.96) 4.50 (4.30-4.70) 27.70 (20.75-36.42) 54.46 7.60
East Asia 19.06 (18.76-19.37) 165.47 (145.14-187.30) 9.89 (9.74-10.05) 23.27 (19.88-27.07) −48.10 −85.94
Eastern Europe 2.13 (2.10-2.16) 8.55 (7.81-9.47) 1.77 (1.75-1.80) 1.52 (1.21-1.88) −16.68 −82.22
Eastern Sub-Saharan Africa 12.35 (12.16-12.54) 74.62 (64.54-85.04) 17.09 (16.83-17.37) 67.22 (51.93-87.25) 38.39 −9.92
High-income Asia Pacific 1.13 (1.10-1.17) 2.81 (2.50-3.26) 0.88 (0.86-0.90) 0.49 (0.42-0.56) −22.58 −82.52
High-income North America 4.74 (4.70-4.78) 13.01 (12.37-13.74) 4.72 (4.65-4.78) 6.84 (6.21-7.58) −0.47 −47.40
North Africa and Middle East 15.07 (14.77-15.41) 178.79 (152.22-212.21) 16.57 (16.24-16.92) 59.66 (47.21-74.22) 9.91 −66.63
Oceania 0.22 (0.21-0.23) 1.47 (1.08-1.90) 0.40 (0.37-0.42) 2.36 (1.57-3.44) 80.72 60.39
South Asia 58.10 (57.12-59.18) 438.60 (381.57-506.46) 46.85 (45.96-47.71) 233.42 (193.68-282.73) −19.37 −46.78
Southeast Asia 12.77 (12.56-12.98) 119.38 (106.73-134.46) 9.63 (9.50-9.78) 44.54 (35.85-54.34) −24.56 −62.69
Southern Latin America 0.57 (0.51-0.63) 7.36 (6.81-7.89) 0.55 (0.53-0.58) 2.31 (1.75-2.96) −2.63 −68.64
Southern Sub-Saharan Africa 2.13 (2.09-2.17) 10.19 (8.54-11.99) 2.22 (2.17-2.26) 11.11 (8.63-14.66) 4.06 9.00
Tropical Latin America 4.14 (4.06-4.22) 47.02 (40.98-54.29) 3.71 (3.65-3.77) 11.31 (8.98-13.98) −10.38 −75.95
Western Europe 3.45 (3.38-3.52) 9.91 (9.44-10.60) 3.19 (3.12-3.27) 3.21 (2.69-3.80) −7.44 −67.65
Western Sub-Saharan Africa 12.40 (12.27-12.54) 91.68 (78.21-105.92) 21.50 (21.23-21.78) 141.95 (114.66-175.77) 73.32 54.83

Abbreviations: GBD, Global Burden of Disease; NA, not applicable; SDI, sociodemographic index; UI, uncertainty interval.