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. 2022 May 31;176(8):787–796. doi: 10.1001/jamapediatrics.2022.1622

Table 2. ASIRs and ASMRs of Neonatal Preterm Birth in 1990 and 2019 and Their Change Trends From 1990 to 2019.

Characteristic No. (95% UI) No. (95% CI)
1990 2019 1990-2019
ASIR per 100 000 ASMR per 100 000 ASIR per 100 000 ASMR per 100 000 EAPC of ASIR EAPC of ASMR
Overall 244.19 (242.43 to 246.14) 19.34 (17.77 to 21.09) 234.96 (233.32 to 236.54) 10.24 (8.66 to 12.18) −0.19 (−0.27 to −0.11) −2.09 (−2.20 to −1.99)
Sex
Female 230.89 (228.39 to 233.63) 17.65 (16.13 to 19.34) 223.07 (220.56 to 225.23) 8.94 (7.60 to 10.46) −0.17 (−0.25 to −0.09) −2.27 (−2.37 to −2.17)
Male 256.64 (254.13 to 259.16) 20.92 (19.02 to 23.05) 246.06 (243.90 to 248.33) 11.46 (9.60 to 13.84) −0.20 (−0.29 to −0.12) −1.96 (−2.06 to −1.86)
SDI region
Low 323.61 (319.41 to 328.41) 22.25 (19.71 to 25.19) 294.30 (290.56 to 297.85) 14.53 (11.89 to 17.83) −0.32 (−0.39 to −0.25) −1.32 (−1.38 to −1.26)
Low-middle 302.97 (298.14 to 308.52) 26.25 (23.62 to 29.45) 255.10 (250.61 to 259.26) 13.96 (11.58 to 16.52) −0.63 (−0.72 to −0.55) −1.94 (−2.06 to −1.82)
Middle 202.36 (200.41 to 204.43) 18.23 (16.88 to 19.66) 194.49 (192.43 to 196.65) 7.26 (6.13 to 8.58) −0.17 (−0.20 to −0.14) −3.02 (−3.21 to −2.83)
Middle-high 174.85 (172.29 to 177.46) 13.58 (12.32 to 14.91) 173.43 (171.06 to 175.93) 3.69 (3.13 to 4.34) −0.09 (−0.12 to −0.06) −4.60 (−4.75 to −4.45)
High 171.30 (169.70 to 173.01) 5.57 (5.24 to 5.94) 183.62 (181.60 to 185.68) 2.27 (2.02 to 2.54) 0.25 (0.13 to 0.38) −2.91 (−3.00 to −2.82)
GBD region
Andean Latin America 190.40 (181.83 to 199.54) 18.96 (16.49 to 21.71) 171.80 (164.88 to 179.11) 6.47 (4.65 to 8.69) −0.49 (−0.54 to −0.44) −3.56 (−3.77 to −3.35)
Australasia 142.27 (135.63 to 149.31) 4.28 (3.96 to 4.68) 153.62 (144.93 to 162.26) 1.42 (1.13 to 1.73) 0.28 (0.17 to 0.39) −3.05 (−3.44 to −2.66)
Caribbean 298.98 (290.28 to 307.94) 14.00 (12.19 to 16.05) 314.89 (303.19 to 326.29) 9.84 (7.11 to 13.39) 0.12 (0.08 to 0.17) −1.08 (−1.18 to −0.98)
Central Asia 149.96 (144.96 to 154.52) 9.98 (8.71 to 11.38) 139.38 (134.69 to 144.10) 6.24 (5.11 to 7.61) −0.33 (−0.37 to −0.30) −1.35 (−1.73 to −0.96)
Central Europe 150.55 (147.39 to 153.64) 9.67 (9.13 to 10.28) 156.82 (154.09 to 159.69) 2.33 (1.77 to 2.94) 0.12 (0.09 to 0.14) −4.80 (−5.05 to −4.54)
Central Latin America 177.97 (174.66 to 181.34) 16.70 (14.71 to 18.70) 192.96 (188.98 to 196.81) 5.48 (4.19 to 6.90) 0.30 (0.26 to 0.34) −3.82 (−3.99 to −3.64)
Central Sub-Saharan Africa 228.14 (218.60 to 237.69) 20.24 (15.48 to 25.90) 211.19 (201.75 to 220.77) 13.01 (9.75 to 17.12) −0.23 (−0.28 to −0.17) −1.25 (−1.42 to −1.08)
East Asia 158.41 (155.99 to 161.05) 13.74 (12.05 to 15.55) 133.45 (131.36 to 135.55) 3.12 (2.66 to 3.63) −0.76 (−0.89 to −0.63) −5.32 (−5.60 to −5.05)
Eastern Europe 151.65 (149.30 to 153.94) 6.06 (5.54 to 6.71) 163.86 (161.57 to 165.90) 1.40 (1.11 to 1.72) 0.36 (0.33 to 0.38) −5.35 (−5.70 to −5.00)
Eastern Sub-Saharan Africa 290.05 (285.64 to 294.45) 17.63 (15.25 to 20.11) 253.36 (249.44 to 257.46) 9.98 (7.71 to 12.95) −0.48 (−0.60 to −0.35) −1.86 (−1.96 to −1.76)
High-income Asia Pacific 119.85 (116.45 to 123.67) 2.96 (2.62 to 3.43) 132.50 (129.47 to 135.80) 0.73 (0.64 to 0.83) 0.46 (0.36 to 0.56) −4.27 (−4.53 to −4.02)
High-income North America 215.56 (213.75 to 217.53) 5.90 (5.61 to 6.24) 233.97 (230.81 to 237.18) 3.38 (3.07 to 3.75) 0.26 (0.07 to 0.46) −1.62 (−1.74 to −1.50)
North Africa and Middle East 268.82 (263.45 to 274.73) 31.99 (27.24 to 37.99) 284.77 (279.15 to 290.74) 10.24 (8.10 to 12.73) 0.17 (0.15 to 0.20) −3.72 (−3.83 to −3.61)
Oceania 205.92 (194.46 to 217.48) 13.87 (10.20 to 17.87) 201.21 (188.27 to 213.86) 12.01 (8.01 to 17.48) −0.09 (−0.14 to −0.04) −0.35 (−0.44 to −0.26)
South Asia 338.16 (332.46 to 344.46) 25.62 (22.31 to 29.57) 292.10 (286.55 to 297.51) 14.56 (12.08 to 17.64) −0.52 (−0.60 to −0.45) −1.64 (−1.77 to −1.50)
Southeast Asia 211.47 (208.08 to 214.93) 19.80 (17.70 to 22.30) 184.13 (181.59 to 186.93) 8.51 (6.85 to 10.38) −0.48 (−0.49 to −0.46) −2.84 (−2.93 to −2.74)
Southern Latin America 113.24 (102.07 to 125.58) 14.67 (13.56 to 15.71) 119.31 (113.65 to 124.75) 4.97 (3.77 to 6.37) 0.25 (0.22 to 0.28) −3.50 (−3.63 to −3.37)
Southern Sub-Saharan Africa 289.10 (283.41 to 295.04) 13.85 (11.61 to 16.29) 278.40 (272.49 to 284.35) 13.95 (10.84 to 18.42) −0.16 (−0.24 to −0.08) 0.62 (0.20 to 1.03)
Tropical Latin America 241.73 (237.41 to 246.47) 27.50 (23.97 to 31.76) 239.95 (236.52 to 243.71) 7.30 (5.79 to 9.02) 0.02 (−0.01 to 0.04) −4.48 (−4.59 to −4.37)
Western Europe 154.83 (151.70 to 158.09) 4.43 (4.22 to 4.74) 154.27 (150.64 to 157.90) 1.54 (1.29 to 1.83) −0.01 (−0.04 to 0.01) −3.45 (−3.60 to −3.31)
Western Sub-Saharan Africa 290.02 (286.89 to 293.26) 21.51 (18.35 to 24.85) 274.32 (270.86 to 277.93) 18.14 (14.65 to 22.46) −0.19 (−0.22 to −0.16) −0.48 (−0.55 to −0.41)

Abbreviations: ASIR, age-standardized incidence rate; ASMR, age-standardized mortality rate; EAPC, estimated annual percentage change; GBD, Global Burden of Disease; SDI, sociodemographic index; UI, uncertainty interval.