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. 2022 May 18;13:861540. doi: 10.3389/fendo.2022.861540

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Copyright © 2022 Zhang, Fu, Zheng, Song, Chen, Jiang, Xing, Hu, Ye, Zhang, Yan and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Patient 1 relapsed 50 months after the first surgery. The tumor located in the sellar and suprasellar regions demonstrated inhomogeneous hyperintensity on coronal T2WI, and the bilateral cavernous sinuses were involved (A). On sagittal T1WI images, the lesion exhibited inhomogeneous hypointensity and irregular margins (B), with significant inhomogeneous enhancement on enhanced T1WI (C). Histologically, there were some atypical or anaplastic features, including focal necrosis (D, H&E, ×100) and microvascular proliferation (E, H&E,×200), with a high Ki-67 index (F, ×200).