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. 2022 May 18;12:844527. doi: 10.3389/fonc.2022.844527

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Copyright © 2022 Du, Qiu, Lu, Zhu, Kong, Xu, Zhang, Tang, Chen, Li, Li, He, Gu, Wang, Qiu and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene alterations of 118 pancreatic cancer patients. (A) The mutation profiles. The panel shows the matrix of mutations with each type of mutation in a different color. Each column denotes an individual tumor and each row represents a gene. The right panel shows the name of mutations and the left panel shows the proportion of mutations. Green; Substitution/Indel, Red; Gene amplification, Blue; Gene homozygous deletion, Yellow; Fusion/Rearrangement, Purple; Truncation. (B) Ratio of different mutation types in KRAS gene. (C) The distribution map of KRAS gene mutation sites showing the distribution of mutation sites.