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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Xenotransplantation. 2021 Oct 13;28(6):e12715. doi: 10.1111/xen.12715

TABLE 5.

Summary of renal interstitial immunoglobulin depositions

Baboon V-C3c V-C4d V-IgM V-IgG PTC-C3c PTC-C4d PTC-IgM PTC-IgG
Group 1: Kidney is not from a CMAHKO pig
B9315 0.5 0.5 0.5 0 0.9 0.5 0.1 0
B17315 0.25 n/a 0 0 2.0 n/a 0.1 0.08
B17615 0.38 n/a 0 0.42 0.9 n/a 0 0.03
B10815 0.15 1.44 0.16 0.43 0.1 1.1 0.1 1.5
B5916 0.5 1.25 1.28 0.08 1.0 0.9 1.7 0.26
Median 0.38 1.25 0.16 0.08 0.9 0.83 0.1 0.08
Group 2: S is from a CMAHKO pig
B8216 0.5 1.3 0.7 0.50 2.5 1.35 2.3 1.2
B1417 0.76 1.11 0.87 0.77 2.0 1.19 1.4 0.88
B3917 0.67 0.7 0.89 0.5 0.2 0.03 0.9 1.0
B15816 0.56 1.13 0.83 0.35 0.8 0.89 0.8 0.31
B517 0.58 1.48 0.47 0.64 1.83 1.61 1.4 1.0
Median 0.58 1.13 0.83 0.5 1.83 1.19 1.4 1.0
p value 0.017 >0.99 0.21 0.019 0.36 0.31 0.046 0.18

Note: Data presented are the average score for each individual animal.

Abbreviations: PTC-C3c, peritubular capillary C3c deposition; PTC-C4d, peritubular capillary C4d deposition; PTC-IgG, peritubular capillary IgG deposition; PTC-IgM, peritubular capillary IgM deposition; V, renal arterial C3c deposition; V-IgG, renal arterial IgG deposition; V-IgM, renal arterial IgM deposition. Median values, range and non-parametric statistical significance (Mann–Whitney U test).