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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Xenotransplantation. 2021 Oct 13;28(6):e12715. doi: 10.1111/xen.12715

TABLE 6.

Summary of major gross and histopathological findings in the ureter

Baboon Histopathological findings Dilation Stricture formation Surgical correction
Group 1: Kidney is not from a CMAHKO pig
B9315 Submucosal edema, fibrosis, and mononuclear cell infiltrates Yes Yes Yes
B17315 Submucosal edema, fibrosis, and mononuclear cell infiltrates Yes No No
B17615 Transmural fibrosis, edema, segmental necrosis, and intimal arteritis Yes Yes Yes
B10815 Transmural fibrosis, edema, fibrin thrombi (muscularis and serosal layers), and intimal arteritis Yes Yes No
B5916 Submucosal edema, fibrosis, fibrin thrombi, and intimal arteritis No* No No
Group 2: Kidney is from a CMAHKO pig
B8216 Submucosal and serosal edema, serosal fat necrosis, fibrin thrombi and multifocal foci of hemorrhage No No No
B1417 Submucosal edema, fibrosis, and mononuclear cell infiltrates No No No
B3917 Submucosal edema, congestion, and fibrin thrombi Yes No No
B15816 Submucosal edema Yes No No
B517 Submucosal and serosal edema and mononuclear cell infiltrates Yes No No
*

Baboon 5916, ureter mucosa appeared thickened, but not dilated on ultrasound examination.