TABLE 6.
Baboon | Histopathological findings | Dilation | Stricture formation | Surgical correction |
---|---|---|---|---|
Group 1: Kidney is not from a CMAHKO pig | ||||
B9315 | Submucosal edema, fibrosis, and mononuclear cell infiltrates | Yes | Yes | Yes |
B17315 | Submucosal edema, fibrosis, and mononuclear cell infiltrates | Yes | No | No |
B17615 | Transmural fibrosis, edema, segmental necrosis, and intimal arteritis | Yes | Yes | Yes |
B10815 | Transmural fibrosis, edema, fibrin thrombi (muscularis and serosal layers), and intimal arteritis | Yes | Yes | No |
B5916 | Submucosal edema, fibrosis, fibrin thrombi, and intimal arteritis | No* | No | No |
Group 2: Kidney is from a CMAHKO pig | ||||
B8216 | Submucosal and serosal edema, serosal fat necrosis, fibrin thrombi and multifocal foci of hemorrhage | No | No | No |
B1417 | Submucosal edema, fibrosis, and mononuclear cell infiltrates | No | No | No |
B3917 | Submucosal edema, congestion, and fibrin thrombi | Yes | No | No |
B15816 | Submucosal edema | Yes | No | No |
B517 | Submucosal and serosal edema and mononuclear cell infiltrates | Yes | No | No |
Baboon 5916, ureter mucosa appeared thickened, but not dilated on ultrasound examination.