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Antitumor activity of MIS-1 on subcutaneous tumorigenesis of LUSC cells in nude mice. After culturing NCI-H226 cells, the cells were inoculated subcutaneously in nude mice to form tumor tissue; the mice received the indicated concentration of MSI-1 by oral administration. The results are shown as (A) tumor tissue images; (B,C) tumor quantitative analysis results of tissue size and weight; (D) Heat map of the inhibition rate of MSI-1 on related factor levels in tumor tissue.
