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. 2022 May 19;15:100296. doi: 10.1016/j.mtbio.2022.100296

Fig. 2.

Fig. 2

Cytotoxicty, synoviocytes migration, and synoviocytes invasion. Cell viability (n ​= ​3) of L929 (a), HUVEC (b), and RA-FLS (c) cocultured with Nap-GFFY and Nap-GDFDFDY hydrogels. Cytotoxicty (n ​= ​3) of MTX-GFFY and MTX-GDFDFDY hydrogels toward L929 (d), HUVEC (e), and RA-FLS (f). (g) Wound-healing assay of RA-FLS with different treatments. (h) Transwell study of RA-FLS treated with different hydrogels. Quantitative analysis (n ​= ​6) of migration rates at 12 ​h (i) and 24 ​h (j). (k) Quantitative analysis (n ​= ​6) of cell numbers in transwell assay. Data are presented as means ​± ​SD. ∗p ​< ​0.05, ∗∗p ​< ​0.01, #p ​< ​0.001, ##p ​< ​0.0001 compared to MTX-GDFDFDY group. Scale bar ​= ​500 ​μm.