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. 2022 May 20;12(3):83–91. doi: 10.5662/wjm.v12.i3.83

Table 1.

Coronavirus disease 2019 main diagnostic methods characteristics

Ref.
Diagnostic method
Sensitivity
Specificity
Time to result
Liu et al[23] ELISA (IgM/IgG) 57.9%-90.7% No cross-reactivity observed About 100 min
Cai et al[24] CLIA (IgM/IgG/IgM and IgG) 57.2%-81.5% No cross-reactivity observed ND
Montesinos et al[25] LFA (IgM/IgG/IgM and IgG) ~70.0% 95.8%-100% About 10 min
Scohy et al[52] Antigen detection 30.2% 100% About 15 min
Porte et al[54] Antigen detection 93.9% 100% About 15 min
Suo et al[19] RT-PCR 94.0% 100% ND
Österdahl et al[26] RT-LAMP 80.0% 73%–100% About 25 min
Dao Thi et al[27] RT-LAMP 97.5% 99.7% About 30 min
Ai et al[28] Chest CT 97.0% 25% ND

ELISA: Enzyme-linked immunosorbent assay; IgA: Immunoglobulin A; IgM: Immunoglobulin M; IgG: Immunoglobulin G; LFA: Lateral flow assay; CLIA: Chemiluminescence immunoassay; RT-PCR: Reverse transcription-polymerase chain reaction; RT-LAMP: Reverse transcription loop-mediated isothermal amplification; CT: Computed tomography; ND: Not described.