Table 1.

Functional enrichment in the queried network (query input UBE2C, UBE2T, UBE2S, TP53)

UBE2 genes			Biological process
	UBE2T	UBE2S	Protein K27-linked ubiquitination
	UBE2T	UBE2S	Protein K29-linked ubiquitination
UBE2C		UBE2S	Free ubiquitin chain polymerization
	UBE2T	UBE2S	Protein K6-linked ubiquitination
UBE2C		UBE2S	Exit from mitosis
UBE2C		UBE2S	Positive regulation of ubiquitin protein ligase activity
UBE2C	UBE2T	UBE2S	Protein K11-linked ubiquitination
UBE2C	UBE2T		Protein K48-linked ubiquitination
	UBE2T	UBE2S	Protein K63-linked ubiquitination
UBE2C		UBE2S	Anaphase-promoting complex-dependent catabolic proceed
UBE2			Cellular component and uniport annotated keywords
UBE2C		UBE2S	Anaphase-promoting complex
UBE2C	UBE2T	UBE2S	Nucleoplasm
UBE2C	UBE2T	UBE2S	ATP-binding
UBE2C		UBE2S	Cell cycle
UBE2C	UBE2T	UBE2S	Transferase
UBE2C	UBE2T	UBE2S	Ubl conjugation
UBE2			Reactome pathways
UBE2C		UBE2S	Aberrant regulation of mitotic exit in cancer due to RB1 defects
UBE2C		UBE2S	APC-Cdc20 mediated degradation of Nek2A
UBE2C		UBE2S	APC/C:Cdc20 mediated degradation of Cyclin B
UBE2C		UBE2S	APC/C: Cdh1 mediated degradation of Cdc20 and other APC/C
UBE2C		UBE2S	Cell cycle checkpoints
UBE2C		UBE2S	Cell cycle, mitotic
UBE2C		UBE2S	Cellular responses to stress
UBE2C		UBE2S	Cellular Senescence
UBE2C		UBE2S	Conversion from APC/C: Cdc20 to APC/C: Cdh1 in late anaphase
UBE2C		UBE2S	Generic transcription pathway
UBE2C		UBE2S	Inactivation of APC/C via direct inhibition of the APC/C compel
UBE2C		UBE2S	Phosphorylation of the APC/C
UBE2C	UBE2T	UBE2S	Post-translational protein modification
UBE2C	UBE2T	UBE2S	Synthesis of active ubiquitin: roles of E1 and E2 enzymes
UBE2C		UBE2S	Synthesis of DNA
UBE2C		UBE2S	Transcriptional regulation by VENTX

UBE2: Ubiquitin-conjugating enzyme 2; APC/C: Anaphase-promoting complex/cyclosome; VENTX: Ventral-expressed homeobox (VENT)-like homeobox protein 2.