Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 18;10:884467. doi: 10.3389/fcell.2022.884467

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Abreu de Oliveira, El Laithy, Bruna, Annibali and Lluis.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The developing mammary gland and Wnt signaling activity. (A) The first morphogenic event in murine mammary gland embryonic development is the specification of the mammary lines along the anterior-posterior axis of each flank around embryonic day 10.5. On embryonic day 11.5, five pairs of placodes composed of condensed mammary epithelial cells arise from the mammary line. These primordial structures undergo a series of morphological changes until a rudimentary mammary ductal tree is formed at E18.5. (B) TOPGAL Wnt reporter expression during embryonic mammary gland development (Wnt active areas in red) (Chu et al., 2004). (C) TOP lacZ Wnt reporter expression during embryonic mammary gland development (Wnt active areas in red) (Boras-Granic et al., 2006; Boras-Granic and Wysolmerski, 2008).