Table 3.
FVC of 79 patients with lower limb onset ALS.
| Groups | Gender ratio, male:female |
Onset age
(years) |
Diagnostic delay (months) | ALSFRS-R score | FVC of predicted, (%) | FVC <80%, n (%) |
|---|---|---|---|---|---|---|
| FLS (n =16) | 1.7:1 | 48.8 ± 8.7 | 23.5 (5,60) | 41.2 ± 4.6 | 90.4 ± 14.5 | 2 (12.5) |
| Typical LL onset | ||||||
| ALS (n = 63) | 1.5:1 | 53.0 ± 10.9 | 11 (2,42)* | 36.5 ± 6.3* | 85.2 ± 16.4 | 27 (42.9)* |
| Statistics | 0.025† | 1.450‡ | 3.341§ | 2.829‡ | 1.164‡ | 5.061† |
| p | 0.873 | 0.151 | 0.001 | 0.006 | 0.248 | 0.024 |
Values are presented as n (%), mean ± SD or median (minimum, maximum).
*p-value for the contrast of variables between patients with FLS and typical patients with lower limb onset ALS; p < 0.05, as compared with patients with FLS. χ2-values;
‡t-values;
§Z-values. FVC, forced vital capacity; ALS, amyotrophic lateral sclerosis; ALSFRS-R, ALS Functional Rating Scale-Revised; FLS, flail leg syndrome; LL, lower limb; SD, standard deviation.