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. 2022 May 31;21:88. doi: 10.1186/s12933-022-01507-7

Fig. 4.

Fig. 4

Multivariable-adjusted hazard ratios for A All-cause death, B CV death and C MACCEs based on restricted cubic spines for the TyG index. Red lines represented references for hazard ratios, and red areas represent 95% confidence intervals. The model was adjusted for age, sex, TyG index, body mass index, systolic blood pressure, diastolic blood pressure, heart rate, HbA1C, C-creative protein, hematocrit, red blood cell distribution width, BNP, sodium, albumin, creatinine, uric acid, ALB, HDL-C, LVEF, history of hypertension, ischemic cardiomyopathy, diabetes mellitus, valvular heart disease, atrial fibrillation, hyperlipidemia, and statin, aldosterone antagonist, digoxin, diuretic, β-blocker, antiplatelet agent, ACEI/ARB/ARNI, insulin, sodium-glucose contrasporter-2 inhibitor, and metformin uses