Table 2.
Unadjusted and adjusted HRs related to 1-year mortality according to IgG subclass deficiency
| Type of IgG deficiency | Number at risk | 1-year mortality | Unadjusted model | Adjusted model* | ||
|---|---|---|---|---|---|---|
| Unadjusted HR (95% CI) | p value | Adjusted HR (95% CI) | p value | |||
| IgG1 deficiency | 9 | 55.6% (5/9) | 3.80 (1.54– 9.41) | 0.004 | 3.92 (1.55–9.87) | 0.004 |
| IgG2 deficiency† | 59 | 27.1% (16/59) | 1.36 (0.79–2.33) | 0.265 | NA† | NA† |
| IgG3 deficiency | 21 | 23.8% (5/21) | 1.29 (0.52–3.20) | 0.577 | 1.27 (0.51–3.15) | 0.612 |
| IgG4 deficiency | 55 | 30.9% (17/55) | 1.65 (0.97–2.79) | 0.063 | 1.74 (1.02–2.98) | 0.043 |
Data are presented as number, percentage, or ratios (95% CIs)
HR hazard ratio, IgG immunoglobulin G, CI confidence interval
*Adjusted for age, sex, ethnicity (white vs. other ethnicities), smoking status (current vs. non-current), asthma status, and cardiac comorbidity status
†The proportional hazards assumption was not met