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. 2022 May 31;23:207. doi: 10.1186/s12859-022-04739-2

Table 3.

Probability of declaring equivalence (pr(Rej) for the normal test, prB(Rej) for the bootstrap test) when the simulated dissimilarity is equal to the equivalence limit, dS=d0.

nSim dS d0 p11 p01 p10 pr(Rej) prB(Rej) E(ν)
100000 0.2857 0.2857 0.01250 0.005 0.005 0.0590 0.0498 225.00
100000 0.2857 0.2857 0.01875 0.005 0.010 0.0570 0.0499 337.50
100000 0.2857 0.2857 0.02500 0.010 0.010 0.0560 0.0502 450.00
100000 0.2857 0.2857 0.06875 0.005 0.050 0.0534 0.0485 1237.50
100000 0.2857 0.2857 0.07500 0.010 0.050 0.0532 0.0500 1350.00
100000 0.2857 0.2857 0.12500 0.050 0.050 0.0527 0.0503 2250.00
100000 0.2857 0.2857 0.13125 0.005 0.100 0.0524 0.0499 2362.50
100000 0.2857 0.2857 0.13750 0.010 0.100 0.0524 0.0502 2475.00
100000 0.2857 0.2857 0.18750 0.050 0.100 0.0522 0.0503 3375.00
100000 0.2857 0.2857 0.25000 0.100 0.100 0.0519 0.0502 4500.00
100000 0.2857 0.2857 0.25625 0.005 0.200 0.0518 0.0501 461.25
100000 0.2857 0.2857 0.26250 0.010 0.200 0.0516 0.0501 4725.00
100000 0.2857 0.2857 0.31250 0.050 0.200 0.0513 0.0499 5625.00
100000 0.2857 0.2857 0.37500 0.100 0.200 0.0513 0.0499 6750.00
100000 0.2857 0.2857 0.50000 0.200 0.200 0.0512 0.0501 9000.00

n=10000 stands for the total number of GO terms, with pij probabilities of enrichment. E(ν) is the expected total number of enriched terms. nsim corresponds to the number of effective simulation replicates to obtain prB(Rej) (nsim×B test computations, B=10000; pr(Rej) was based on 106 simulation replicates)