Table 3.
Results of multiple regression analysis with the Delirium Rating Scale, Revised-98-Thai (DRS) scores at day 1, day 2 and day 3 as dependent variables and immune/cytokine profiles as explanatory variables while allowing for the effects of demographic/clinical data
| Dependent variables | Explanatory variables | β | t | p | F model | df | p | R2 |
|---|---|---|---|---|---|---|---|---|
| # 1 DRS day 1 | Model | 10.03 | 3/61 | < 0.001 | 0.330 | |||
| CNS disease | 0.450 | 4.26 | < 0.001 | |||||
| IL-8—day 1 | 0.263 | 2.51 | 0.015 | |||||
| BMI | -0.262 | -2.49 | 0.016 | |||||
| #2 DRS day 2 | Model | 9.13 | 3/60 | < 0.001 | 0.313 | |||
| BMI | -0.283 | -2.61 | 0.011 | |||||
| T cell growth—day1 | 0.732 | 4.13 | < 0.001 | |||||
| IL-4 – day 1 | -0.558 | -3.13 | 0.003 | |||||
| #3 DRS day 2 | Model | 7.84 | 4/57 | < 0.001 | 0.355 | |||
| Th1—day 2 | 0.397 | 3.54 | < 0.001 | |||||
| Age | 0.370 | 3.19 | 0.002 | |||||
| sIL-1RA—day 2 | -0.289 | -2.48 | 0.016 | |||||
| CNS disease | 0.228 | 2.12 | 0.039 | |||||
| #4 DRS day 3 | Model | 11.88 | 1/63 | < 0.001 | 0.159 | |||
| IRS/CIRS—day 2 | 0.398 | 3.45 | < 0.001 | |||||
| #5 Mean DRS days 1—3 | Model | 5.51 | 2/61 | 0.006 | 0.153 | |||
| IL-6—day 1 | 0.313 | 2.65 | 0.010 | |||||
| BMI | -0.244 | -2.07 | 0.043 |
CNS Central nervous system, IL interleukin, BMI body mass index, Th T helper, IRS/CIRS immune-inflammatory response system / compensatory immunoregulatory system ratio