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. 2022 May 31;22:369. doi: 10.1186/s12888-022-04021-y

Table 4.

Result of multiple regression analysis with the Delirium Rating Scale, Revised-98-Thai (DRS) scores at day 1, day 2 or day 3 as dependent variables and immune/cytokine profiles and baseline DRS scores as explanatory variables

Dependent variables Explanatory variables B t p F model df p R2
#1 DRS day 1 Model - - - 14.42 6/58  < 0.001 0.599
DRS—baseline 0.527 6.12  < 0.001
IL-8—day 1 0.383 3.80  < 0.001
CIRS—day 1 -0.362 -2.42 0.019
T cell growth—day 1 0.477 3.11 0.003
IL-4—day 1 -0.526 -3.06 0.003
TNF-α—day 1 0.331 2.58 0.012
# 2 DRS day 2 Model 12.04 3/58  < 0.001 0.384
DRS—baseline 0.413 3.98  < 0.001
Th1—day 2 0.486 4.33  < 0.001
IL-4—day 2 -0.236 -2.09 0.041
#3 DRS day 2 Model 8.46 3/60  < 0.001 0.297
Age 0.2665 2.21 0.031
Th1—day 1 0.288 2.65 0.010
DRS—baseline 0.275 2.29 0.026
#4 DRS day 3 Model 11.99 2/62  < 0.001 0.279
IRS/CIRS—day 2 0.369 3.41 0.001
DRS—baseline 0.348 3.22 0.002
#5 Mean DRS days 1–3 Model 14.78 3/60  < 0.001 0.425
DRS—baseline 0.414 3.83  < 0.001
Age 0.300 2.77 0.008
T cell growth—day 1 0.222 2.26 0.027

IL interleukin, IRS/CIRS immune-inflammatory response system / compensatory immunoregulatory system, TNF tumor necrosis factor, Th T helper