Table 2.
Clinical characteristics of participants with different LVMI changes
| Total | LVMI-regression N = 113 | Stable N = 31 | LVMI-progression N = 72 | P value | |
|---|---|---|---|---|---|
| Age | 55.3 ± 16.8 | 54.2 ± 16.8 | 60.1 ± 16.4 | 55. 2 ± 17.0 | 0.785 |
| Male, n(%) | 130(60.2%) | 65(57.5%) | 18(58.1%) | 42(64.6%) | 0.557 |
| BMI (kg/m2) | 23.1 ± 3.5 | 22.6 ± 3.3 | 24.2 ± 3.1 | 23.7 ± 3.6 | 0.047 |
| SBP (mmHg) | 135 ± 14 | 134 ± 14 | 135 ± 15 | 138 ± 15 | 0.124 |
| DBP (mmHg) | 82 ± 8 | 81 ± 9 | 80 ± 8 | 84 ± 10 | 0.021 |
| MAP | 99.6 ± 9.2 | 98.3 ± 8.8 | 98.7 ± 8.3 | 102.1 ± 9.7 | 0.018 |
| History of smoking | 45(20.8%) | 23(20.4%) | 8(25.8%) | 13(20.0%) | 0.754 |
| History of diabetes | 53(24.5%) | 29(25.7%) | 4(12.9%) | 20(30.8%) | 0.253 |
| Use of statins | 42(19.4%) | 21(18.6%) | 6(19.4%) | 15(23.1%) | 0.931 |
| Use of anti-hypertensive drugs | 200(92.6%) | 103(91.2%) | 28(90.3%) | 69(65.8%) | 0.436 |
| Use of RAAS antagonists | 93(43.1%) | 51(45.1%) | 11(35.5%) | 30(46.2%) | 0.130 |
| Dialysis-related variables | |||||
| CAPD, n(%) | 202(93.5%) | 106(93.8%) | 27(87.1%) | 69(95.8%) | 0.251 |
| nPCR (g/kg/24 h) | 0.93 ± 0.18 | 0.94 ± 0.17 | 0.91 ± 0.15 | 0.92 ± 0.18 | 0.647 |
| Urinary output(L/24 h) | 0.86(0.50,1.28) | 0.83(0.46,1.28) | 0.83(0.67, 1.14) | 0.92(0.57,1.29) | 0.858 |
| Total Ccr (L/week) | 67.5(57.1, 81.8) | 67.7(57.5,84.0) | 68.2(54.6, 88.7) | 66.8(57.4,79.5) | 0.733 |
| Residual renal Ccr (L/week) | 31.3(18.9, 46.5) | 32.4(20.1,49.6) | 30.5(15.5,52.7) | 31.2(18.8,42.9) | 0.609 |
| Total Kt/V | 1.93(1.72,2.22) | 1.94(1.71,2.26) | 1.98(1.70,2.16) | 1.88(1.73,2.15) | 0.539 |
| Residual renal Kt/V | 0.61(0.36, 0.88) | 0.61(0.35,0.92) | 0.61(0.35,0.88) | 0.62(0.42,0.87) | 0.984 |
| Proportion of 1.5%-glucose dialysate(%) | 88.9(69.4,100) | 88.9(67.8,100) | 80.6(66.7,100) | 91.7(75.0,100) | 0.770 |
| Volume of dialysate(L/24 h) | 6.27(5.82, 7.59) | 6.19(5.83,7.53) | 6.40(5.92,7.44) | 6.30(5.73,7.68) | 0.917 |
| Biochemical parameters | |||||
| Hemoglobin (g/L) | 100.0 ± 13.8 | 101.8 ± 13.7 | 99.9 ± 13.7 | 96.6 ± 13.8 | 0.055 |
| Ferritin (ng/ml) | 233.1(153.8, 327.3) | 256.0(163.7,343.2) | 207.1(157.0,267.7) | 205.8(138.7,307.3) | 0.033 |
| Serum iron (umol/L) | 12.3(10.1, 15.1) | 13.3(10.6,15.3) | 12.1(10.4,14.5) | 11.6(9.2,14.3) | 0.129 |
| Iron saturation (%) | 31.7(26.0, 38.0) | 32.7(27.3, 39.7) | 31.7(27.7, 36.0) | 28.3(24.0,34.3) | 0.059 |
| Albumin (g/L) | 35.8 ± 4.4 | 36.3 ± 4.7 | 34.8 ± 4.2 | 35.3 ± 4.0 | 0.184 |
| Calcium (mmol/L) | 2.15 ± 0.17 | 2.15 ± 0.18 | 2.16 ± 0.15 | 2.14 ± 0.14 | 0.812 |
| Phosphate (mmol/L) | 1.53(1.32, 1.79) | 1.56 ± 0.32 | 1.55 ± 0.36 | 1.61 ± 0.40 | 0.513 |
| iPTH (pg/mL) | 284.1(186.6, 393.7) | 302.3(203.7,423.3) | 208.5(156.4,332.3) | 283.8(180.8,388.4) | 0.139 |
| CHO (mmol/L) | 4.40 ± 0.91 | 4.46 ± 0.99 | 4.22 ± 0.80 | 4.40 ± 0.83 | 0.439 |
| TG (mmol/L) | 1.62(1.25, 2.28) | 1.64(1.23, 2.57) | 1.54(1.32, 2.33) | 1.64(1.22, 2.29) | 0.994 |
| LDL (mmol/L) | 2.29(1.92, 2.71) | 2.25(1.88,2.73) | 2.29(1.74,2.59) | 2.32(2.08,2.70) | 0.311 |
| HDL (mmol/L) | 0.94(0.80, 1.12) | 0.97(0.84,1.15) | 0.84(0.76,1.03) | 0.90(0.77,1.09) | 0.036 |
| ApoA1 (g/L) | 0.99(0.89, 1.12) | 1.01(0.94, 1.15) | 0.93(0.86, 1.09) | 0.96(0.86, 1.06) | 0.009 |
| ApoB (g/L) | 0.69 ± 0.15 | 0.69 ± 0.16 | 0.68 ± 0.14 | 0.70 ± 0.14 | 0.822 |
| NT-proBNP (per 1000 pg/ml) | 2.26(0.93, 7.47) | 1.95(0.80,7.58) | 2.28(1.46,5.23) | 2.50(1.15,8.93) | 0.428 |
| hsCRP (mg/L) | 1.65(0.79, 4.12) | 1.33(0.61,3.73) | 2.11(1.12,4.40) | 1.96(1.12,5.40) | 0.032 |
| FIB (g/L) | 3.72(3.26, 4.31) | 3.64(3.13,4.13) | 3.85(3.34,4.36) | 3.88(3.45, 4.59) | 0.014 |