TABLE 3.
Amino acid changes in the FepR protein.
| Listadapt id | Position/amino acid change in FepR |
Biocide adaptation | |||||||||||||
| EGD-e (lmo2088) | 19 | 22 | 27 | 37 | 44 | 46 | 100 | 103 | 108 | 116 | 121 | 130 | 157 | 168 | |
| Phe | Thr | Ile | Ser | Asp | Asp | Trp | Tyr | Pro | Gln | Glu | Phe | Gly | Tyr | ||
| FR-BIO-DC-501 | Ile | DDAC | |||||||||||||
| FR-BIO-BC-503 | Stop | BC | |||||||||||||
| FR-BIO-DC-504 | FS | DDAC | |||||||||||||
| FR-BIO-DC-508 | Stop | DDAC | |||||||||||||
| FR-BIO-DC-506 | Stop | DDAC | |||||||||||||
| CZ-BIO-BC-277 | Tyr | BC | |||||||||||||
| CZ-BIO-CD-278 | Stop | DDAC | |||||||||||||
| NO-BIO-BC-41 | Leu | BC | |||||||||||||
| CZ-BIO-BC-283 | Thr | BC | |||||||||||||
| CZ-BIO-CD-284 | Leu | DDAC | |||||||||||||
| CZ-BIO-BC-287 | Gly | BC | |||||||||||||
| CZ-BIO-CD-288 | Stop | DDAC | |||||||||||||
| IT-BIO-CD-139 | Tyr | DDAC | |||||||||||||
| NL-BIO-BC-66 | Leu | BC | |||||||||||||
| NL-BIO-CD-67 | Stop | DDAC | |||||||||||||
Positions in orange correspond to the HTH domain and position in green locates in the vicinity of the ligand-binding pocket. Missense mutations are indicated in blue and the frameshift (FS) and premature stop codon (Stop) are indicated in red.