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Kaplan–Meier estimates of 5-year overall survival for p16 IHC (A), HPV RNA-ISH (B), HPV DNA-ISH (C), HPV DNA-PCR (D), combined p16 IHC/HPV DNA-PCR (E), and combined p16 IHC/HPV RNA-ISH (F). Global differences in survival curves were compared through use of the log-rank test.
