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. 2022 Jun 1;100(6):skac045. doi: 10.1093/jas/skac045

Table 1.

Calculations1 for blood flow, nutrient uptake, nutrient utilization, and quotients

Blood flow (3H2O tracer)
Rinf3H2O (dpm/min) Pump rate ∗ [infusate]
Racc(f) (dpm/min) αpl slope ∗ (0.8 ∗ fetal weight)
Racc(m) (dpm/min) Racc(f) + [αpl slope ∗ 0.8(uterine weight)]
Umbilical Blood Flow (UBF; mL/min) (Rinf − Racc(f))/ ([3H2O]α(WB) − [3H2O]γ(WB))
Umbilical Plasma Flow (UPF; mL/min) UBF ∗ [1 − Hctf(avg)]
Uterine Blood Flow (UtBF; mL/min) (Rinf − Racc(m))/ ([3H2O]V(WB) − [3H2O]A(WB))
Uterine Plasma Flow (UtPF; mL/min) UtBF ∗ [1 − Hctm(avg)]
Nutrient uptake and utilization rates
Umbilical Oxygen Uptake (fetal oxygen utilization; UOU; mmol/min) UBF ∗ ([O2]γ(WB) − [O2]α(WB))
Uterine Oxygen Uptake (UtOU; mmol/min) UtBF ∗ ([O2]A(WB) − [O2]V(WB))
Uteroplacental Oxygen Utilization (mmol/min) UtOU − UOU
Plasma to WB Glucose Conversion [G]pl ∗ [1 − (0.24 ∗ Hct)] − (3.3 ∗ Hct)
Umbilical Glucose Uptake (UGU; µmol/min) UBF ∗ ([G]γ(WB) − [G]α(WB))
Uterine Glucose Uptake (UtGU; µmol/min) UtBF ∗ ([G]A(WB) − [G]V(WB))
Uteroplacental Glucose Utilization (µmol/min) UtGU − UGU
Umbilical Lactate Uptake (µmol/min; ULU) UBF ∗ ([L]γ(pl) − [L]α(pl))
Uterine Lactate Secretion (µmol/min; UtLS) UtBF ∗ ([L]V(pl) − [L]A(pl))
Uteroplacental Lactate Production (µmol/min) ULU + UtLS
Umbilical AA Uptake (µmol/min; UAAU) UPF ∗ ([AA]γ(pl) − [AA]α(pl))
Uterine AA Uptake (µmol/min; UtAAU) UtPF ∗ ([AA]A(pl) − [AA]V(pl))
Umbilical AA Carbon Uptake (µmol/min; UCU) (#AA carbons) ∗ UAAU
Uterine AA Carbon Uptake (µmol/min; UtCU) (#AA carbons) ∗ UtAAU
Umbilical AA Nitrogen Uptake (µmol/min; UNU) (#AA nitrogens) ∗ UAAU
Uterine AA Nitrogen Uptake (µmol/min; (UtNU) (#AA nitrogens) ∗ UtAAU

Calculations are derived from Cilvik et al. (2021).