Table 1.
Blood flow (3H2O tracer) | |
Rinf3H2O (dpm/min) | Pump rate ∗ [infusate] |
Racc(f) (dpm/min) | αpl slope ∗ (0.8 ∗ fetal weight) |
Racc(m) (dpm/min) | Racc(f) + [αpl slope ∗ 0.8(uterine weight)] |
Umbilical Blood Flow (UBF; mL/min) | (Rinf − Racc(f))/ ([3H2O]α(WB) − [3H2O]γ(WB)) |
Umbilical Plasma Flow (UPF; mL/min) | UBF ∗ [1 − Hctf(avg)] |
Uterine Blood Flow (UtBF; mL/min) | (Rinf − Racc(m))/ ([3H2O]V(WB) − [3H2O]A(WB)) |
Uterine Plasma Flow (UtPF; mL/min) | UtBF ∗ [1 − Hctm(avg)] |
Nutrient uptake and utilization rates | |
Umbilical Oxygen Uptake (fetal oxygen utilization; UOU; mmol/min) | UBF ∗ ([O2]γ(WB) − [O2]α(WB)) |
Uterine Oxygen Uptake (UtOU; mmol/min) | UtBF ∗ ([O2]A(WB) − [O2]V(WB)) |
Uteroplacental Oxygen Utilization (mmol/min) | UtOU − UOU |
Plasma to WB Glucose Conversion | [G]pl ∗ [1 − (0.24 ∗ Hct)] − (3.3 ∗ Hct) |
Umbilical Glucose Uptake (UGU; µmol/min) | UBF ∗ ([G]γ(WB) − [G]α(WB)) |
Uterine Glucose Uptake (UtGU; µmol/min) | UtBF ∗ ([G]A(WB) − [G]V(WB)) |
Uteroplacental Glucose Utilization (µmol/min) | UtGU − UGU |
Umbilical Lactate Uptake (µmol/min; ULU) | UBF ∗ ([L]γ(pl) − [L]α(pl)) |
Uterine Lactate Secretion (µmol/min; UtLS) | UtBF ∗ ([L]V(pl) − [L]A(pl)) |
Uteroplacental Lactate Production (µmol/min) | ULU + UtLS |
Umbilical AA Uptake (µmol/min; UAAU) | UPF ∗ ([AA]γ(pl) − [AA]α(pl)) |
Uterine AA Uptake (µmol/min; UtAAU) | UtPF ∗ ([AA]A(pl) − [AA]V(pl)) |
Umbilical AA Carbon Uptake (µmol/min; UCU) | (#AA carbons) ∗ UAAU |
Uterine AA Carbon Uptake (µmol/min; UtCU) | (#AA carbons) ∗ UtAAU |
Umbilical AA Nitrogen Uptake (µmol/min; UNU) | (#AA nitrogens) ∗ UAAU |
Uterine AA Nitrogen Uptake (µmol/min; (UtNU) | (#AA nitrogens) ∗ UtAAU |
Calculations are derived from Cilvik et al. (2021).