Table 5.

Sex and Gender Self-Report Questions From Alzheimer’s Disease Research Centers (ADRCs) and Investigator-Initiated (II) Cohort Study Protocols

Sex/gender question	ADRCsa (n = 13)	II cohort studiesb (n = 19)
Subject’s sex:
1. Male	10	14
2. Female
Subject’s sex:
What sex do you consider yourself?	0	1
1. Male
2. Female
3. Don’t know
4. Refused
Gender:
Please select your gender identity:	0	2
1. Male
2. Female
Genderf:
Please select your gender identity:	1	0
1. Male
2. Female
3. Nonbinary/genderfluid
Sex at birthf:
What was your sex at birth?	2	0
1. Female
2. Male
Sexual orientationc,f:
What is your sexual orientation?	2	0
1. Bisexual
2. Gay
3. Lesbian
4. Straight (heterosexual)
5. Questioning or unsure
6. Other
7. Prefer not to answer
No written protocol	1	0
Unknown/unclear	1e	0
Secondary sourcesd	0	2

Notes: Number of responses may exceed number of reporting entities as some ADRCs and investigator-initiated cohort studies had multiple questions in their protocols.

^aTwelve protocols from ADRCs survey responses and one additional ADRCs protocols obtained via online public source.

^bSix protocols from investigator-initiated cohort study personnel survey responses and 13 additional investigator-initiated cohort study protocols obtained via online public source.

^cIn one instance, item was proposed but not yet included in assessment battery.

^dWhile sexual orientation is a construct distinct from sex and gender, this table shows all self-report measures submitted for the current study.

^eCoordinator intake: “Coordinators obtain study consent and, if applicable, brain donation consent ... Participant demographics and family history are also tabulated.”

^fObtained from an existing source such as medical record, insurance record, or other secondary record.