Table 1.
Comparison of serum GSH, CAT, SOD, and 8OH-dG levels between groups.
| Groups | GSH (mmol/L) | CAT (U/L) | SOD (IU/Ml) | 8-OHdG (pg/ml) |
|---|---|---|---|---|
| Control | 240.93 ± 27.49b | 18.39 ± 0.40a,b | 0.63 ± 0.03a | 1.24 ± 0.093c |
| Cisplatin | 161.48 ± 17.72c | 15.91 ± 1.43b | 0.15 ± 0.08e | 1.86 ± 0.28a |
| Cis + gal | 244.59 ± 9.58b | 17.09 ± 4.68a,b | 0.30 ± 0.02c,d,e | 1.31 ± 0.13b,c |
| Cis + sly | 214.96 ± 44.56b | 15.18 ± 1.98b | 0.28 ± 0.10d,e | 1.75 ± 0.29a,b |
| Cis + sly + gal | 237.21 ± 23.40b | 22.32 ± 2.56a | 0.27 ± 0.13d,e | 1.78 ± 0.31a,b |
| Silymarin | 287.32 ± 27.93a | 20.93 ± 2.92a,b | 0.58 ± 0.28a,b | 1.57 ± 0.40a,b,cb |
| Gallic acid | 290.21 ± 18.82a | 17.42 ± 5.25a,b | 0.52 ± 0.10a,b,c | 1.43 ± 0.19a,b,c |
| Gal + sly | 252.96 ± 31.66a,b | 22.73 ± 0.83a | 0.39 ± 0.10b,c,d | 1.29 ± 0.46b,c |
a, b, and c: the statistical difference between groups with different letters in the same column is significant (p < 0.05). Control: control group; cisplatin: cisplatin group; cis + gal: cisplatin + gallic acid; cis + sly: cisplatin + silymarin; cis + sly + gal: cisplatin + gallic acid + silymarin; silymarin: silymarin group; gallic acid: gallic acid group; gal + sly: gallic acid + silymarin.