Table 2.
Groups | GSH (mmol/L) | CAT (U/L) | SOD (IU/Ml) | MDA (mmol/L) | 8-OHdG (pg/ml) |
---|---|---|---|---|---|
Control | 137.94 ± 21.17b,c | 27.04 ± 2.64a | 1.69 ± 0.43a,b | 0,70 ± 0.22d | 2.27 ± 0.33c |
Cisplatin | 109.71 ± 10.56d | 18.83 ± 4.00b | 1.13 ± 0.37b | 2.07 ± 0,21a | 3.91 ± 0.65a |
Cis + gal | 151.22 ± 5.72a,b | 25.82 ± 1.16a | 1.90 ± 0.30a | 1,01 ± 0,13c | 2.68 ± 0.45b,c |
Cis + sly | 164.59 ± 5.51a | 24.22 ± 3.09a,b | 1.90 ± 0.47a | 1,45 ± 0,41b | 2.56 ± 0.11b,c |
Cis + sly + gal | 132.41 ± 18.51b,c,d | 22.38 ± 3.34a,b | 2.33 ± 0.73a | 1,12 ± 0,07c | 2.63 ± 0.72b,c |
Silymarin | 144.76 ± 17.91a,b,c | 22.43 ± 3.81a,b | 1.96 ± 0.36a | 0,99 ± 0,26c | 2.99 ± 0.22b,c |
Gallic acid | 124.92 ± 16.74c,d | 26.41 ± 2.46a | 1.60 ± 0.32a,b | 1,24 ± 0,09b,c | 2.73 ± 0.56b,c |
Gal + sly | 136.30 ± 15.06b,c | 23.53 ± 5.80a,b | 1.66 ± 0.58a,b | 1,44 ± 0,19b | 2.68 ± 0.45b |
a, b, c, d, and e: the statistical difference between groups with different letters in the same column is significant (p < 0.05). Control: control group; cisplatin: cisplatin group; cis + gal: cisplatin + gallic acid; cis + sly: cisplatin + silymarin; cis + sly + gal: cisplatin + gallic acid + silymarin; silymarin: silymarin group; gallic acid: gallic acid group; gal + sly: gallic acid + silymarin.