Table 3.
Comparison of GSH, CAT, SOD, MDA, and 8OH-dG levels in kidney tissue between groups.
| Groups | GSH (mmol/L) | CAT (U/L) | SOD (IU/Ml) | MDA (mmol/L) | 8-OHdG (pg/ml) |
|---|---|---|---|---|---|
| Control | 135.96 ± 30.46a | 30.60 ± 3.38a | 2.44 ± 0.27a,b | 1,36 ± 0,21b,c,d | 2.19 ± 0.38e |
| Cisplatin | 106.10 ± 27.46a | 20.67 ± 3.45c | 1.73 ± 0.33c | 2.30 ± 0,21a | 4.66 ± 0.47a |
| Cis + gal | 167.53 ± 28.96a | 24.23 ± 2.45b,c | 2.38 ± 0.38a,b | 1,13 ± 0,07d,e | 3.05 ± 0.11b,c,d |
| Cis + sly | 162.82 ± 37.01a | 25.54 ± 5.80b,c | 2.30 ± 0.47a,b | 1,57 ± 0,01b | 3.78 ± 0.46b |
| Cis + sly + gal | 128.87 ± 24.80a | 22.27 ± 1.50b,c | 2.87 ± 0,41a | 1,10 ± 0,08e | 3.30 ± 0.86b,c,d |
| Silymarin | 142.57 ± 25.14a | 23.65 ± 1.26b,c | 2.40 ± 0.42a,b | 1,25 ± 0,17c,d,e | 3.75 ± 0.31b,c |
| Gallic acid | 112.04 ± 100.11a | 26.19 ± 1.76a,b | 2.43 ± 0.34a,b | 1,45 ± 0,77b,c | 2.92 ± 0.25d,e |
| Gal + sly | 136.09 ± 13.92a | 23.16 ± 2.16b,c | 2.23 ± 0.18b,c | 1,13 ± 0,27d,e | 2.95 ± 0.61c,d,e |
a, b, and c: the statistical difference between groups with different letters in the same column is significant (p < 0.05). Control: control group; cisplatin: cisplatin group; cis + gal: cisplatin + gallic acid; cis + sly: cisplatin + silymarin; cis + sly + gal: cisplatin + gallic acid + silymarin; silymarin: silymarin group; gallic acid: gallic acid group; gal + sly: gallic acid + silymarin.