Table 5.
Groups | AST (IU/L) | ALT (IU/L) | Urea (mg/dl) | Creati̇ni̇ne (mg/dl) | Albumin (g/dl) | Globulin (g/dl) | Total protein (g/dl) |
---|---|---|---|---|---|---|---|
Control | 108.20 ± 12.47a,b | 32.00 ± 3.05a | 53.80 ± 6.97c,d | 0.48 ± 0.04b | 28.40 ± 2.7a,b | 28.60 ± 3.05b | 57.00 ± 5.29a |
Cisplatin | 124.67 ± 6.65a | 35.67 ± 3.78a | 74.67 ± 6.65a | 2.41 ± 0.37a | 26.33 ± 1.15a,b | 29.00 ± 3.60b | 55.33 ± 4.50a |
Cis + gal | 94.00 ± 24.52b | 23.60 ± 7.60a | 57.50 ± 3.69c,d | 0.59 ± 0.08b | 25.00 ± 1.58b | 31.20 ± 6.83a,b | 56.20 ± 6.09a |
Cis + sly | 96.40 ± 10.47a,b | 30.60 ± 8.38a | 62.20 ± 9.52b,c | 0.62 ± 0.22b | 26.80 ± 1.78a,b | 29.60 ± 1.34a,b | 56.40 ± 3.05a |
Cis + sly + gal | 110.80 ± 38.88a,b | 35.80 ± 12.91a | 70.80 ± 13.44a,b | 0.72 ± 0.36b | 26.00 ± 3.60a,b | 34.60 ± 4.03a | 60.60 ± 4.98a |
Silymarin | 89.83 ± 10.96b | 33.17 ± 6.96a | 40.83 ± 5.63e | 0.44 ± 0.02b | 29.17 ± 0.75a | 29.67 ± 1.03a,b | 58.83 ± 0.98a |
Gallic acid | 95.00 ± 9.21b | 32.00 ± 5.29a | 48.50 ± 8.42d,e | 0.45 ± 0.04b | 28.50 ± 0.57a,b | 29.75 ± 0.50a,b | 58.25 ± 0.95a |
Gal + sly | 100.50 ± 5.91a,b | 29.75 ± 9.77a | 56.67 ± 2.51c,d | 0.49 ± 0.05b | 29.25 ± 3.59a | 32.00 ± 1.15a,b | 61.25 ± 4.34a |
a, b, and c: the statistical difference between groups with different letters in the same column is significant (p < 0.05). Control: control group; cisplatin: cisplatin group; cis + gal: cisplatin + gallic acid; cis + sly: cisplatin + silymarin; cis + sly + gal: cisplatin + gallic acid + silymarin; silymarin: silymarin group; gallic acid: gallic acid group; gal + sly: gallic acid + silymarin.