Table 5.

Logistic Regression Model Suggest That Impaired In Vitro Neutrophil Phagocytosis of Pseudomonas aeruginosa Isolates Is Associated With Failed Eradication Therapy in Patients With Cystic Fibrosis

Unadjusted Model
		OR		(95% CI)		P Value
In vitro neutrophil phagocytosis		0.76		(.62–.94)		.01
In vitro neutrophil intracellular bacterial killing		0.76		(.66–1.01)		.06
Adjusted Modela
	OR	(95% CI)	P Value	Variablea	OR	(95% CI)	P Value
In vitro neutrophil phagocytosis	0.76	(.62–.94)	.01	Age	0.91	(.67–1.25)	.57
	0.76	(.62–.94)	.01	Female sex	1.27	(.19–8.58)	.81
	0.76	(.60–.95)	.02	Age at diagnosis >2 y	0.85	(.06–12.43)	.91
	0.73	(.57–.95)	.02	Heterozygous	0.76	(.06–9.05)	.83
				Other	2.01	(.13–33.8)	.61
	0.77	(.62–.95)	.02	BMI	0.82	(.54–1.23)	.33
	0.71	(.56–.92)	<.01	Pancreatic insufficiency	0.02	(.00–3.23)	.14
	0.76	(.62–.94)	.01	CFRD	0.67	(.01–36.72)	.84
	0.76	(.61–.94)	.01	FEV1 %, predicted	1	(.96–1.05)	.94
	0.77	(.63–.95)	.01	Mucoidy	0.39	(.05–2.74)	.34
	0.79	(.63–.90)	.04	Twitching	0.96	(.87–1.06)	.38

Abbreviations: BMI, body mass index; CFRD, cystic fibrosis–related diabetes mellitus; CI, confidence interval; FEV₁, forced expiratory volume in 1 second; OR, odds ratio.

^aIn the adjusted model, each additional clinical parameter or bacterial phenotype was included 1 at a time. P = .05, with OR evaluated using a 2-sided .05 level of significance.