Figure 16. Somatosensory feedback is required for proper paw placement during skilled locomotion.
A) Cat stepping on a horizontal ladder before (control) and after a complete cutaneous denervation of the hindpaws. Experimental results from (93). B) Egr3 mutant mice make more errors during walking on a horizontal ladder, determined as more frequent foot droppings between rungs than in wild types. Each bar indicates the number of steps that landed on a rung (black bars) or missed the rung (red bars) counted during one run. Each set of bar represents a run from different mouse (n = 13 for wild type and n = 15 for Egr3 mutants). Reproduced and modified from (10).