Table 2.
Univariate Analysis of Clinical and Pathological Variables Associated With Event-Free Survival
| Variable | N | Events | Event-Free survival (%) | |||
|---|---|---|---|---|---|---|
| Years | HR | P | ||||
| 5 | 10 | |||||
| Age at RT | ||||||
| ≤8 Y | 88 | 27 | 77.0 (68.7–86.4) | 70.7 (61.3–81.6) | ||
| >8 Y | 90 | 19 | 82.2 (74.7–90.5) | 77.2 (68.3–87.2) | 0.7 (0.4–1.3) | .22 |
| Histological subtype | ||||||
| Classic/desmoplastic | 152 | 37 | 82.1 (76.2–88.4) | 75.2 (68.1–83.2) | ||
| Anaplastic | 26 | 9 | 65.4 (49.4–86.5) | 65.4 (49.4–86.5) | 1.6 (0.8–3.4) | .18 |
| Sex | ||||||
| Male | 103 | 32 | 76.7 (69.0–85.3) | 69.2 (60.0–79.7) | ||
| Female | 75 | 14 | 83.7 (75.7–92.6) | 80.1 (71.2–90.2) | 0.6 (0.3–1.1) | .072 |
| Extent of resectiona | ||||||
| GTR/NTR | 159 | 39 | 80.5 (74.5–86.9) | 75.3 (68.3–83.0) | ||
| STR | 18 | 7 | 70.8 (52.3–96.0) | 57.7 (38.0–87.7) | 1.9 (0.8–4.2) | .12 |
| RT duration (days) | ||||||
| ≤45 | 151 | 40 | 80.0 (73.8–86.6) | 72.8 (65.3–81.1) | ||
| >45 | 27 | 6 | 77.8 (63.6–95.2) | 77.8 (63.6–95.2) | 0.8 (0.3–1.8) | .54 |
| Risk | ||||||
| Standard | 102 | 20 | 87.2 (81.0–94.0) | 79.5 (71.1–88.9) | ||
| Intermediate/High | 76 | 26 | 69.3 (59.7–80.6) | 66.2 (56.3–78.0) | 2.1 (1.1–3.7) | .014 |
Abbreviations: GTR, gross total resection; HR, hazard ratio; NTR, near total resection; RT, radiotherapy; STR, subtotal resection.
aThis analysis excludes 1 patient with biopsy only.