Table 3.
Univariate Analysis of Clinical and Pathological Variables Associated with Overall Survival
| Variable | N | Deaths | Overall Survival (%) | |||
|---|---|---|---|---|---|---|
| Years | HR | P | ||||
| 5 | 10 | |||||
| Age at RT | ||||||
| ≤8 Y | 88 | 22 | 80.4 (72.4–89.2) | 75.8 (66.9–85.8) | ||
| >8 Y | 90 | 14 | 87.3 (80.5–94.6) | 83.0 (75.2–91.7) | 0.6 (0.3–1.2) | .17 |
| Histological subtype | ||||||
| Classic/desmoplastic | 152 | 27 | 87.2 (82.0–92.7) | 81.7 (75.3–88.7) | ||
| Anaplastic | 26 | 9 | 65.0 (48.9–86.4) | 65.0 (48.9–86.4) | 2.3 (1.1–4.8) | .030 |
| Sex | ||||||
| Male | 103 | 26 | 80.1 (72.6–88.3) | 73.2 (64.3–83.2) | ||
| Female | 75 | 10 | 89.1 (82.3–96.5) | 87.7 (80.4–95.6) | 0.5 (0.2–1.0) | .058 |
| Extent of resectiona | ||||||
| GTR/NTR | 159 | 30 | 84.6 (79.2–90.5) | 81.0 (74.7–87.8) | ||
| STR | 18 | 6 | 76.0 (58.0–99.6) | 61.0 (40.3–92.2) | 2.0 (0.8–4.8) | .11 |
| RT duration (days) | ||||||
| ≤45 | 151 | 32 | 83.1 (77.3–89.4) | 78.5 (71.7–85.9) | ||
| >45 | 27 | 4 | 88.6 (77.2–100.0) | 84.1 (70.9–99.8) | 0.7 (0.2–1.8) | .41 |
| Risk | ||||||
| Standard | 102 | 14 | 91.0 (85.6–96.8) | 86.9 (79.9–94.4) | ||
| Intermediate/high | 76 | 22 | 74.1 (64.7–84.9) | 68.9 (58.7–80.8) | 2.5 (1.3–4.8) | .0068 |
Abbreviations: GTR, gross total resection; HR, hazard ratio; NTR, near total resection; RT, radiotherapy; STR, subtotal resection.
aThis analysis excludes 1 patient with biopsy only.