Table 1.
Summary of Key Cohort Characteristics, Overall and Event Free Survival Times
| Demographic Variable | Final Cohort (n = 74) | |
|---|---|---|
| Resection | GTR | 33 |
| STR | 41 | |
| Gender | Male | 38 |
| Female | 36 | |
| Age (years) | Median | 7.8 |
| Range | 3.1–18.8 | |
| Site | PF | 47 |
| ST | 27 | |
| WHO Grade | 2 | 39 |
| 3 | 35 | |
| DNA Methylation Analysis | PFA | 17 |
| ZFTA | 10 | |
| PFB | 5 | |
| YAP | 1 | |
| ST_PLAGL1 | 1 | |
| 1q Status | Gain | 18 |
| No gain | 42 | |
| Follow-up (years) | Median | 10.0 |
| Range | 0.17–19.00 | |
| Follow-up of Survivors (years) | Median | 12.4 |
| Range | 1.16–19.00 | |
| Event Free Survival (%) 95% CI |
5-year | 49.5 |
| 39.3–62.4 | ||
| 10-year | 46.7 | |
| 36.5–59.7 | ||
| Overall Survival (%) 95% CI |
5-year | 69.3 |
| 59.4–80.9 | ||
| 10-year | 60.5 | |
| 50.1–73.1 | ||
Abbreviations: CI, Confidence Interval; GTR, Gross Total Resection; STR, Subtotal Resection; PF, Posterior fossa; ST, Supratentorial. PLAGL1: Neuroepithelial tumour, PLAGL1-fusion positive.